Prognostic factors for progression‐free and overall survival in malignant pleural mesothelioma

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Prognostic factors and survival in malignant pleural mesothelioma.

Malignant pleural mesothelioma is a lethal disease and little is known about prognostic factors. The prognostic significance of age, stage of disease, gender and histological subtype was studied in 167 new cases of cytologically (15%) or histologically (85%) proven malignant pleural mesothelioma in the Rotterdam area, during the period 1987-1989. Median survival of all patients was 242 days. Un...

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1558pa New Prognostic Index for Overall Survival in Malignant Pleural Mesothelioma.

Y. Kataoka1, Y. Yamamoto1, T. Otsuki2, M. Shinomiya3, T. Terada4, M. Hirabayashi3, T. Nakano4, S. Fukukuhara1 Healthcare Epidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, JAPAN Cancer Center, Hyogo College of Medicine, Nishinomiya, JAPAN Respiratory Medicine, Hyogo Prefectural Amagasaki Hospital, Amagasaki, JAPAN Division of Respiratory Medicine, Hyogo Colleg...

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Survival in Good Performance Malignant Pleural Mesothelioma Patients; Prognostic Factors and Predictors of Response

Purpose: Malignant pleural mesothelioma (MPM) has a poor prognosis in general. Here we sought to evaluate prognostic factors and predictors of response to chemotherapy in good performance (PS=0-I) patients. Methods: We retrospectively reviewed our database and enrolled patients with MPM who received platinum containing chemotherapy (2012-2014). Clinico-pathological and laboratory data were retr...

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A new prognostic index for overall survival in malignant pleural mesothelioma: the rPHS (regimen, PS, histology or stage) index.

OBJECTIVE Existing prognostic indices for malignant pleural mesothelioma do not incorporate the recent advances in oncology care. The purpose of this study was to provide a prognostic index for overall survival in malignant pleural mesothelioma patients treated with chemotherapy with pemetrexed or best supportive care in the recent clinical setting. METHODS A retrospective cohort study was pe...

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SMO expression level correlates with overall survival in patients with malignant pleural mesothelioma

BACKGROUND Malignant mesothelioma is an aggressive, treatment-resistant tumor arising from mesothelium of pleura, peritoneum and pericardium. Despite current combined regimen, its prognosis remains dismal, calling for more effective targeted therapies. We investigated whether aberrant Hh activation may play a role in mesothelioma. METHODS SMO and SHH expression levels were analyzed in 46 meso...

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ژورنال

عنوان ژورنال: Thoracic Cancer

سال: 2021

ISSN: 1759-7706,1759-7714

DOI: 10.1111/1759-7714.13814